Federico Fenaroli

Førsteamanuensis i biologisk kjemi

Federico Fenaroli

Kontakt

E-post: federico.fenaroli@uis.no

Organisasjonsenhet

Det teknisk-naturvitenskapelige fakultet

Institutt for kjemi, biovitenskap og miljøteknologi

Publikasjoner

Vitenskapelige publikasjoner

Dal, Nils-Jørgen; Schäfer, Gabriela; Thompson, Andrew; Schmitt, Sascha; Redinger, Natalja; Alonso Rodriguez, Noelia; Johann, Kerstin; Ojong, Jessica; Wohlmann, Jens; Best, Andreas; Koynov, Kaloian; Zentel, Rudolf; Schaible, Ulrich E.; Griffiths, Gareth Wyn; Barz, Matthias; Fenaroli, Federico

(2023)

Π-Π interactions stabilize PeptoMicelle-based formulations of Pretomanid derivatives leading to promising therapy against tuberculosis in zebrafish and mouse models.

Journal of Controlled Release.

ISSN 0168-3659.

Volum 354.

s.851-868.

DOI: 10.1016/j.jconrel.2023.01.037

Bhandari, Madhavi; Soria-Carrera, Héctor; Wohlmann, Jens; Dal, Nils-Jørgen; de la Fuente, Jesús M.; Martín-Rapún, Rafael; Griffiths, Gareth Wyn; Fenaroli, Federico

(2023)

Subcellular localization and therapeutic efficacy of polymeric micellar nanoparticles encapsulating bedaquiline for tuberculosis treatment in zebrafish.

Biomaterials Science.

ISSN 2047-4830.

Volum 11.

Hefte 6.

s.2103-2114.

DOI: 10.1039/d2bm01835

Creamer, Adam; Fiego, Alessandra Lo; Agliano, Alice; Prados-Martin, Lino; Høgset, Håkon; Najer, Adrian; Richards, Daniel A.; Wojciechowski, Jonathan P.; Foote, James E. J.; Kim, Nayoung; Monahan, Amy; Tang, Jiaqing; Shamsabadi, André; Rochet, Léa N. C.; Thanasi, Ioanna A.; de la Ballina, Laura R; Rapley, Charlotte L.; Turnock, Stephen; Love, Elizabeth A.; Bugeon, Laurence; Dallman, Margaret J.; Heeney, Martin; Kramer-Marek, Gabriela; Chudasama, Vijay; Fenaroli, Federico; Stevens, Molly M.

(2023)

Modular Synthesis of Semiconducting Graft Copolymers to Achieve “Clickable” Fluorescent Nanoparticles with Long Circulation and Specific Cancer Targeting.

Advanced Materials.

ISSN 0935-9648.

DOI: 10.1002/adma.202300413

Bauer, Tobias A.; Schramm, Jonas; Fenaroli, Federico; Siemer, Svenja; Seidl, Christine I.; Rosenauer, Christine; Bleul, Regina; Stauber, Roland H.; Koynov, Kaloian; Maskos, Michael; Barz, Matthias

(2023)

Complex Structures Made Simple – Continuous Flow Production of Core Cross-Linked Polymeric Micelles for Paclitaxel Pro-Drug-Delivery.

Advanced Materials.

ISSN 0935-9648.

Volum 35.

Hefte 21.

s.1-9.

DOI: 10.1002/adma.202210704

Dal, Nils-Jørgen Knudsen; Speth, Martin Tobias; Johann, Kerstin; Barz, Matthias; Beauvineau, Claire; Wohlmann, Jens; Fenaroli, Federico; Gicquel, Brigitte; Griffiths, Gareth Wyn; Alonso Rodriguez, Noelia

(2022)

The zebrafish embryo as an in vivo model for screening nanoparticle-formulated lipophilic anti-tuberculosis compounds.

Disease Models and Mechanisms.

ISSN 1754-8403.

Volum 15.

Hefte 1.

DOI: 10.1242/dmm.049147

Czysch, Christian; Medina-Montano, Carolina; Dal, Nils-Jørgen Knudsen; Dinh, Thi; Fröder, Yannick; Winterwerber, Pia; Maxeiner, Konrad; Räder, Hans-Joachim; Schuppan, Detlef; Schild, Hansjörg; Bros, Matthias; Biersack, Bernhard; Fenaroli, Federico; Grabbe, Stephan; Nuhn, Lutz

(2022)

End group dye-labeled polycarbonate block copolymers for micellar (immuno-)drug delivery.

Macromolecular rapid communications.

ISSN 1022-1336.

Volum 43.

Hefte 12.

s.1-10.

DOI: 10.1002/marc.202200095

Najer, Adrian; Belessiotis-Richards, Alexis; Kim, Hyemin; Saunders, Catherine; Fenaroli, Federico; Adrianus, Christopher; Che, Junyi; Tonkin, Renée L.; Høgset, Håkon; Lörcher, Samuel; Penna, Matthew; Higgins, Stuart G.; Meier, Wolfgang; Yarovsky, Irene; Stevens, Molly M.

(2022)

Block Length-Dependent Protein Fouling on Poly(2-oxazoline)-Based Polymersomes: Influence on Macrophage Association and Circulation Behavior.

Small.

ISSN 1613-6810.

Volum 18.

Hefte 27.

DOI: 10.1002/smll.202201993

Trousil, Jiří; Dal, Nils-Jørgen; Fenaroli, Federico; Schlachet, Inbar; Kubíčková, Pavla; Janoušková, Olga; Pavlova, Ewa; Škorič, Miša; Trejbalová, Kateřina; Pavliš, Oto; Sosnik, Alejandro

(2022)

Antibiotic-Loaded Amphiphilic Chitosan Nanoparticles Target Macrophages and Kill an Intracellular Pathogen.

Small.

ISSN 1613-6810.

Volum 18.

Hefte 28.

DOI: 10.1002/smll.202201853

Bouz, Ghada; Šlechta, Petr; Jand'ourek, Ondřej; Konečná, Klára; Paterová, Pavla; Bárta, Pavel; Novák, Martin; Kučera, Radim; Dal, Nils-Jørgen; Fenaroli, Federico; Zemanová, Júlia; Forbak, Martin; Korduláková, Jana; Pavliš, Oto; Kubíčková, Pavla; Doležal, Martin; Zitko, Jan

(2022)

Hybridization Approach Toward Novel Antituberculars: Design, Synthesis, and Biological Evaluation of Compounds Combining Pyrazinamide and 4-Aminosalicylic Acid.

ACS Infectious Diseases.

ISSN 2373-8227.

Volum 9.

Hefte 1.

s.79-96.

DOI: 10.1021/acsinfecdis.2c00433

Resseguier, Julien; Levraud, Jean-Pierre; Dal, Nils-Jørgen Knudsen; Fenaroli, Federico; Primard, Charlotte; Wohlmann, Jens; Carron, Gabrielle; Griffiths, Gareth Wyn; Le Guellec, Dominique; Verrier, Bernard

(2021)

Biodistribution of surfactant-free poly(lactic-acid) nanoparticles and uptake by endothelial cells and phagocytes in zebrafish: Evidence for endothelium to macrophage transfer.

Journal of Controlled Release.

ISSN 0168-3659.

Volum 331.

s.228-245.

DOI: 10.1016/j.jconrel.2021.01.006

Siemer, Svenja; Bauer, Tobias A.; Scholz, Paul; Breder, Christina; Fenaroli, Federico; Harms, Gregory; Dietrich, Dimo; Dietrich, Jörn; Rosenauer, Christine; Barz, Matthias; Becker, Sven; Strieth, Sebastian; Reinhardt, Christoph; Fauth, Torsten; Hagemann, Jan; Stauber, Roland H.

(2021)

Targeting Cancer Chemotherapy Resistance by Precision Medicine-Driven Nanoparticle-Formulated Cisplatin.

ACS Nano.

ISSN 1936-0851.

Volum 15.

Hefte 11.

s.18541-18556.

DOI: 10.1021/acsnano.1c08632

Bauer, Tobias A.; Horvat, Natalie K.; Marques, Oriana; Chocarro, Sara; Mertens, Christina; Colucci, Silvia; Schmitt, Sascha; Carrella, Luca M.; Morsbach, Svenja; Koynov, Kaloian; Fenaroli, Federico; Blümler, Peter; Jung, Michaela; Sotillo, Rocio; Hentze, Matthias W.; Muckenthaler, Martina; Barz, Matthias

(2021)

Core Cross-Linked Polymeric Micelles for Specific Iron Delivery: Inducing Sterile Inflammation in Macrophages.

Advanced Healthcare Materials.

ISSN 2192-2640.

Volum 10.

Hefte 19.

s.1-13.

DOI: 10.1002/adhm.202100385

Dal, Nils-Jørgen Knudsen; Kocere, Agnese; Wohlmann, Jens; Van Herck, Simon; Bauer, Tobias A; Resseguier, Julien; Bagheri Fam, Shahla; Hyldmo, Hilde C Bergvin; Barz, Matthias; De Geest, Bruno G.; Fenaroli, Federico

(2020)

Zebrafish Embryos Allow Prediction of Nanoparticle Circulation Times in Mice and Facilitate Quantification of Nanoparticle–Cell Interactions.

Small.

ISSN 1613-6810.

Volum 16.

Hefte 5.

s.1-12.

DOI: 10.1002/smll.201906719

Kocere, Agnese; Resseguier, Julien; Wohlmann, Jens; Skjeldal, Frode Miltzow; Khan, Shanawaz; Speth, Martin; Dal, Nils-Jørgen Knudsen; Ng, Matthew Yoke Wui; Alonso Rodriguez, Noelia; Scarpa, Edoardo; Rizzello, Loris; Battaglia, Giuseppe; Griffiths, Gareth Wyn; Fenaroli, Federico

(2020)

Real-time imaging of polymersome nanoparticles in zebrafish embryos engrafted with melanoma cancer cells: Localization, toxicity and treatment analysis.

EBioMedicine.

ISSN 2352-3964.

Volum 58.

s.1-12.

DOI: 10.1016/j.ebiom.2020.102902

Fenaroli, Federico; Robertson, James; Scarpa, Edoardo; Gouveia, Virginia; Di Guglielmo, Claudia; De Pace, Cesare; Elks, Philip; Poma, Alessandro; Evangelopoulos, Dimitrios; Julio, Ortiz Canseco; Prajsnar, Tomasz; Marriott, Helen; Dockrell, David; Foster, Simon J; McHugh, Timothy; Renshaw, Stephen; Samiter Marti, Josep; Battaglia, Giuseppe; Rizzello, Loris

(2020)

Polymersomes Eradicating Intracellular Bacteria.

ACS Nano.

ISSN 1936-0851.

Volum 14.

Hefte 7.

s.8287-8298.

DOI: 10.1021/acsnano.0c01870

Vestre, Katharina; Kjos, Ingrid; Guadagno, Noemi Antonella; Distefano, Marita Borg; Kohler, Felix; Fenaroli, Federico; Bakke, Oddmund; Progida, Cinzia

(2019)

Rab6 regulates cell migration and invasion by recruiting Cdc42 and modulating its activity.

Cellular and Molecular Life Sciences (CMLS).

ISSN 1420-682X.

Volum 76.

Hefte 13.

s.2593-2614.

DOI: 10.1007/s00018-019-03057-w

Trousil, Jiří; Syrová, Zdeňka; Dal, Nils-Jørgen Knudsen; Rak, Dmytro; Konefal, Rafal; Pavlova, Ewa; Matejkova, Jana; Cmarko, Dusan; Kubickova, Pavla; Pavlis, Oto; Urbánek, Tomáš; Sedlak, Marian; Fenaroli, Federico; Raška, Ivan; Stepanek, Petr; Hrubý, Martin

(2019)

Rifampicin Nanoformulation Enhances Treatment of Tuberculosis in Zebrafish.

Biomacromolecules.

ISSN 1525-7797.

Volum 20.

Hefte 4.

s.1798-1815.

DOI: 10.1021/acs.biomac.9b00214

Fenaroli, Federico; Repnik, Urska; Xu, Yitian; Johann, Kerstin; Van Herck, Simon; Dey, Pradip; Skjeldal, Frode Miltzow; Frei, Dominik Michael; Fam, Shahla Bagheri; Kocere, Agnese; Haag, Rainer; De Geest, Bruno G.; Barz, Matthias; Russell, David G.; Griffiths, Gareth Wyn

(2018)

Enhanced permeability and retention-like extravasation of nanoparticles from the vasculature into tuberculosis granulomas in zebrafish and mouse models.

ACS Nano.

ISSN 1936-0851.

Volum 12.

Hefte 8.

s.8646-8661.

DOI: 10.1021/acsnano.8b04433

Van Driessche, Alexandra; Kocere, Agnese; Everaert, Hannelien; Nuhn, Lutz; Van Herck, Simon; Griffiths, Gareth Wyn; Fenaroli, Federico; De Geest, Bruno G.

(2018)

pH-sensitive hydrazone-linked doxorubicin nanogels via polymeric-activated ester scaffolds: Synthesis, assembly, and in vitro and in vivo evaluation in tumor-bearing zebrafish.

Chemistry of Materials.

ISSN 0897-4756.

Volum 30.

Hefte 23.

s.8587-8596.

DOI: 10.1021/acs.chemmater.8b03702

Kumar, Sheemal S.; Tandberg, Julia Isabel; Penesyan, Anahit; Elbourne, Liam D. H.; Suarez-Bosche, Nadia; Don, Emily; Skadberg, Eline Supannee Setu; Fenaroli, Federico; Cole, Nicholas; Winther-Larsen, Hanne Cecilie; Paulsen, Ian T.

(2018)

Dual Transcriptomics of Host-Pathogen Interaction of Cystic Fibrosis Isolate Pseudomonas aeruginosa PASS1 With Zebrafish.

Frontiers in Cellular and Infection Microbiology.

ISSN 2235-2988.

DOI: 10.3389/fcimb.2018.00406

Ulanova, Lilia; Pinheiro, Marina; Vibe, Carina Beatrice; Nunes, Clàudia; Misaghian, Dorna; Wilson, Steven Ray Haakon; Zhu, Kaizheng; Fenaroli, Federico; Winther-Larsen, Hanne Cecilie; Reis, Saletta; Griffiths, Gareth

(2017)

Treatment of Francisella infections via PLGA-and lipid-based nanoparticle delivery of antibiotics in a zebrafish model.

Diseases of Aquatic Organisms.

ISSN 0177-5103.

Volum 125.

Hefte 1.

s.19-29.

DOI: 10.3354/dao03129

Evensen, Lasse; Lie Johansen, Patrick; Koster, Gerbrand; Zhu, Kaizheng; Herfindal, Lars; Speth, Martin; Fenaroli, Federico; Hildahl, Jon Paul; Fam, Shahla Bagheri; Tulotta, Claudia; Prasmickaite, Lina; Mælandsmo, Gunhild; Snaar-Jagalska, Ewa; Griffiths, Gareth Wyn

(2016)

Zebrafish as a model system for characterization of nanoparticles against cancer.

Nanoscale.

ISSN 2040-3364.

Volum 8.

Hefte 2.

s.862-877.

DOI: 10.1039/c5nr07289a

Vibe, Carina Beatrice; Fenaroli, Federico; Pires, David; Wilson, Steven Ray Haakon; Bogoeva, Vanya; Kalluru, Raja Sab; Speth, Martin; Anes, Elsa; Griffiths, Gareth; Hildahl, Jon Paul

(2016)

Thioridazine in PLGA nanoparticles reduces toxicity and improves rifampicin therapy against mycobacterial infection in zebrafish.

Nanotoxicology.

ISSN 1743-5390.

Volum 10.

Hefte 6.

s.680-688.

DOI: 10.3109/17435390.2015.1107146

Lie Johansen, Patrick; Fenaroli, Federico; Evensen, Lasse; Griffiths, Gareth; Koster, Gerbrand

(2016)

Optical micromanipulation of nanoparticles and cells inside living zebrafish.

Nature Communications.

ISSN 2041-1723.

Volum 7.

DOI: 10.1038/ncomms10974

Ertunc, Meric Erikci; Sikkeland, Jørgen; Fenaroli, Federico; Griffiths, Gareth Wyn; Daniels, Melissa C.; Cao, Haiming; Saatcioglu, Fahri; Hotamisligil, Gökhan S.

(2015)

Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity.

Journal of Lipid Research.

ISSN 0022-2275.

Volum 56.

Hefte 2.

s.423-434.

DOI: 10.1194/jlr.M055798

Fenaroli, Federico; Westmoreland, David; Benjaminsen, Jørgen; Kolstad, Terje R Selnes; Skjeldal, Frode Miltzow; Meijer, Annemarie H.; van der Vaart, Michiel; Ulanova, Lilia; Roos, Norbert; Nyström, Bo; Hildahl, Jon Paul; Griffiths, Gareth Wyn

(2014)

Nanoparticles as Drug Delivery System against Tuberculosis in Zebrafish Embryos: Direct Visualization and Treatment.

ACS Nano.

ISSN 1936-0851.

Volum 8.

Hefte 7.

s.7014-7026.

DOI: 10.1021/nn5019126

Kalluru, Raja Sab; Fenaroli, Federico; Westmoreland, David; Ulanova, Lilia; Maleki, Atoosa; Roos, Norbert; Madsen, Marie Paulsen; Koster, Gerbrand; Jacobsen, Wolfgang Mathias; Wilson, Steven Ray Haakon; Røberg-Larsen, Hanne; Khuller, Gopal K.; Singh, Amandeep; Nyström, Bo; Griffiths, Gareth Wyn

(2013)

Polylactide-co-glycolide-rifampicin-nanoparticles efficiently clear Mycobacterium bovis BCG infection in macrophages and remain membrane-bound in phago-lysosomes.

Journal of Cell Science.

ISSN 0021-9533.

Volum 126.

Hefte 14.

s.3043-3054.

DOI: 10.1242/jcs.121814

Anna, Lesniak; Fenaroli, Federico; Monopoli, Marco; Åberg, Christoffer; Dawson, Kenneth A.; Salvati, Anna

(2012)

Effects of the Presence or Absence of a Protein Corona on Silica Nanoparticle Uptake and Impact on Cells.

ACS Nano.

ISSN 1936-0851.

Volum 6.

Hefte 7.

s.5845-5857.

DOI: 10.1021/nn300223w

Shapero, Kayle; Fenaroli, Federico; Lynch, Iseult; Cottell, David; Salvati, Anna; Dawson, Kenneth A.

(2011)

Time and space resolved uptake study of silica nanoparticles by human cells.

Molecular Biosystems.

ISSN 1742-206X.

Volum 7.

Hefte 2.

s.371-378.

DOI: 10.1039/c0mb00109k

Bexiga, Mariana; Varela, Juan; Wang, Fengjuan; Fenaroli, Federico; Salvati, Anna; Lynch, Iseult; Simpson, Jeremy; Dawson, Kenneth A.

(2011)

Cationic nanoparticles induce caspase 3-, 7- and 9-mediated cytotoxicity in a human astrocytoma cell line.

Nanotoxicology.

ISSN 1743-5390.

Volum 5.

Hefte 4.

s.557-567.

DOI: 10.3109/17435390.2010.539713